The Great Silk Road is a system of caravan routes of ancient times and in the Middle Ages which connected Asia with the Mediterranean and European world. These routes highly influenced the development of trade interactions and cultural ties between the West and the East. The Silk Road served not only as route for exporting goods such as silk, spices, precious metals, minerals handicrafts, architecture and paintings but also transmitted cultural exchange including theatric performance, dance and music art. The Great Silk Road played moreover a major role in dissemination of religions. The Silk Road can thus be considered as an important fundament of human civilization.