Breast Cancer (BRCA) Challenge
In the framework of its International Basic Science Programme (IBSP) and of its partnership with the Human Variome Project (HVP) the Natural Sciences Sector organises the launch of a new initiative on human genetics research related to women's health: the Breast Cancer (BRCA) Challenge.
The BRCA Challenge of the Global Alliance for Genomics and Health (GA4GH) aims to advance understanding of the genetic basis of breast cancer and related cancers by pooling data on BRCA genetic variants from around the world, bringing together information on sequence variation and clinical features in diverse populations. Improved understanding of genetic variation in these genes has the potential to improve patient diagnoses and prevention of disease. This will provide a model for management of variation across the human genome.
The Human Variome Project (HVP), a member of GA4GH and partner of UNESCO, will facilitate a BRCA Challenge meeting on June 12th and 13th meeting at UNESCO in Paris. The meeting will address ethical and regulatory issues as well as examine issues surrounding data acquisition and variant interpretation. The primary aim of this meeting is to lay foundation for an international Faculty that would focus on BRCA studies on a global scale, especially in developing countries